I was getting the "Game disc could not be read" error all the time.
I then ran my Wiikey config disc and set the drive speed to 3x. Works perfect every time now.
If you are experiencing problems, try this. Obviously this won't work for everyone but it worked for me.
yo guys the sonic x shadow generations trailer dropped today, and shadow just straight up decided, and i hate (love) to bring this dead meme up, but, it's morbin time