Do i need these if i play with the Loader from the SD Card?
Or is this only needed for the R4 etc Carts?
Anti piracy works by detecting differences that become apparent when running as something other than an official game on an official cart. Different things have different requirements, and there is a further quirk.
I would say there are 3 broad scenarios (plus emulation)
1) Old flash cart that did not make it to the end of the DS library/releases before being abandoned. I will also include the "never intended" stuff in this but let us not go there.
2) Good flash cart that did or got a port of a loader that did. (typically supercard, akaio or wood firmwares but there are a few others)
3) This newer stuff with the DSi/3ds acting as a loader for them.
3) occurred long after the DS library had finished but as most patches/fixes were wrapped up in loaders and flash carts it basically had to reinvent them or dump them. I believe various options have since arisen with most of the good stuff integrated but you might find an edge case.
2) should mostly have it sorted without this, however some might not have quite made it to the very end; the DSi and 3ds flash cart blocking updates took their toll. After said updates there were a couple of interesting games released (for most it is probably pokemon conquest and pokemon black and white 2). 1) then benefits a lot from a library of anti piracy patches as it will allow people to play games, DS flash carts were cheap at one point but if you found one in a drawer or something...
The quirk.
Anti piracy comes at a cost in some cases. I will ignore the cheat/extra features thing as it is not really applicable (short version is some of the older "get me through to the update" modes like clean/ghost/pure/whatever would either see cheats trip AP or disable such things entirely which is less than ideal for some. If you have patches though you can get around it) and instead note that some AP was so pervasive that it slowed games down, if said AP was removed it would speed things up beyond even what you would see on a stock game cart. Some things some flash carts did would not remove the AP but instead make it appear as it should (but still have the AP do all it would normally), and I imagine some emulators work like they are hardware and don't remove the AP.