SSRI antidepressants cause sexual dysfunction in many people. There's a 3.6x increased risk for the sexual dysfunction with SSRI antidepressants if your genotype for the rs6311 SNP is C;C. I am not depressed and don't take antidepressants, but if I did require antidepressants, I would not take SSRI antidepressants, since my DNA test shows that I'm C;C for that SNP.