There was this scene in Final Fantasy VIII...can't really remember where, but around the beginning or end of the 3rd CD...
For some reason, one of the characters start telling about how everyone in the party (along with the female antagonist) knew each other in their youth, but for some reason all the other characters couldn't remember it until this guy tells the others about it. It was in some garden...it was all sunny and tranquil...birds were singing...the other characters were in disbelief but couldn't quite deny it...then there was some recalling going on...and flashbacks...
...and I was sitting there behind my PC going "yeah, yeah, yeah...I get it. More plot going on. Why the hell can't I fast-forward this entire monologue? *presses 'next'-button furiously*".
Finally, after about 3 hours of inner musing, inner doubts, denying, accepting and more of that stuff, I was able to actually DO anything.
...and then my computer crashed.
Before I had the chance to save.
AAAARRGGGGGG!!!!!
Another such moment in that game was in that castle somewhere in the last CD. Probably near the end boss or something. Either way, all of the sudden, this magical castle comes and steals just about every stat I've grinded into. Was bad enough by itself...but then I had to fight that antagonist (perhaps even the end boss) who just killed my entire party in 2 turns.
To this very day, fallout is still the only RPG-franchise I can play without getting traumatized.
EDIT: another one...but I think it may be off-topic, as it is not a scene "in a game".
Back in the old days, I was an avid UT2004 player. So when
UT2007 the UT3 demo was released, I was more than eager to play it.
Now...the vehicle thingies was a total overhaul, which was just a disappointment to me. But that was okay (there were plenty of game modes without them).
But the interface was butt-ugly, unintuitive, clunky and barely had any options whatsoever. It was like you had to wade through a whole bunch of not-important screens and visual shit, just to start a game.
But that was okay...Epic (the makers) claimed they were listening to their fans and the demo (released about a month before the actual game) was open to criticism.
So fanboys like me did just that. We pointed out why it was ugly, how it could be improved, why it would be better, and so on. It wasn't as though we asked a lot of complex changes (seriously: how much effort is it to remove a screen that just says "are you sure you want to start the game?"?).
The result: nothing. The game itself still had that same sluggish look and feel about it. Fuck...their multiplayer tabs were so bad you couldn't even find your own clanmates (result: pretty much everyone played on open servers -> FPS veterans just slaughtered newbies, being boring for the former and frustrating for the latter).
It took them almost a year to fix things...and even then, the interface was improved to be "not good, but passable" rather than "absolutely terrible".
Yeah, I cried at that (the former UT series had far better GUI's...it was just one of those things that are so common you don't realise its quality until it's gone).