It depends on the demographic makeup of the state and whatever brings the votes in.Do they just flip a coin on all social issues? There is no consistency from either party.
If you live in a mennonite/amish state such as Pennsylvania, Ohio and Indiana, these people are not going to vote for you if you are pushing the trans or gays laws, If you live in California they would.
Fatcs are that USA is massive and in much the same way the Europe has loads of different countries in it that all hold different ideas and cultures, US states are much the same. What flies in New york as OK behaviouris not going to be the same as in Florida or Texas and vice versa.